Which of the following is NOT a common side effect of statins?

Flushing of the skin is not a common side effect associated with statin medications. Statins primarily exert their effects by inhibiting the enzyme HMG-CoA reductase, critical for cholesterol synthesis in the liver, and while they do have several potential side effects, skin flushing is more commonly linked to other lipid-lowering agents, such as niacin.

Statins are more frequently associated with muscle-related side effects, such as muscle pain or weakness, due to their impact on muscle metabolism. Digestive problems, including nausea, diarrhea, and constipation, are also relatively common in patients taking statins, attributable to gastrointestinal effects on absorption or metabolism. Liver damage, although less frequent, can occur as a serious side effect, which necessitates regular monitoring of liver enzymes during treatment.