Which of the following is a rare but serious side effect of statins?

Myopathy is a rare but serious side effect associated with statin use. Statins are primarily prescribed to lower cholesterol levels and reduce the risk of cardiovascular disease, but they can also impact muscle health. Myopathy refers to muscle pain, weakness, or damage.

In the case of severe muscle damage, a condition known as rhabdomyolysis can develop, which can lead to serious complications such as kidney failure due to the release of muscle breakdown products into the bloodstream. Although myopathy can occur with any statin, certain risk factors such as higher doses or interactions with other medications can increase its likelihood.

Recognizing myopathy is crucial since early diagnosis and discontinuation of the statin may prevent further complications. Monitoring for symptoms of muscle discomfort or weakness is important in patients on statin therapy to ensure safety.