Which of the following is an effect of high triglyceride levels?

High triglyceride levels are associated with significantly increased cardiovascular risk. Elevated triglycerides can contribute to the development of atherosclerosis, which is the buildup of fatty deposits in the arterial walls. This can lead to narrowing of the arteries and may increase the likelihood of serious cardiovascular events, such as heart attacks and strokes.

The link between high triglycerides and cardiovascular disease is well-documented. In addition to the direct effects on arterial health, high triglyceride levels often accompany other metabolic conditions, including insulin resistance and obesity, further exacerbating cardiovascular risk.

While factors such as insulin sensitivity and appetite may be influenced by metabolic states, high triglycerides do not improve insulin sensitivity, nor do they generally lead to decreased appetite. Additionally, high levels of triglycerides are typically not associated with higher HDL (high-density lipoprotein) levels; instead, they often correlate with lower HDL levels, which is also a risk factor for cardiovascular disease. Thus, the most pertinent effect of high triglyceride levels remains the increased risk they pose to cardiovascular health.