What lab test should the nurse expect the provider to order for a client taking fibrate and niacin?

When a client is taking fibrates and niacin, it is important to monitor liver function tests (LFTs). Both fibrates and niacin can impact liver function, and routine monitoring of LFTs helps detect any potential hepatotoxicity early in treatment.

Fibrates, such as gemfibrozil and fenofibrate, are known to potentially cause elevations in liver enzymes due to their effects on lipid metabolism and their impact on the liver. Similarly, niacin can cause liver toxicity, especially at higher doses, and has been associated with hepatic dysfunction. Monitoring LFTs allows for the assessment of liver health and helps guide the ongoing management of the patient's medication regimen.

This proactive approach is crucial, as it ensures that any adverse effects on liver function can be addressed promptly, thus maintaining patient safety while optimizing lipid-lowering therapy. Other tests may monitor different health parameters, but in the context of fibrate and niacin therapy, LFTs are specifically vital.