Name a common side effect associated with statins.

Myopathy is a known and serious side effect associated with statin medications. Statins work by inhibiting the HMG-CoA reductase enzyme, which is crucial for cholesterol synthesis. While they effectively lower cholesterol levels and reduce the risk of cardiovascular events, this mechanism can also disrupt muscle metabolism. As a result, some patients may experience muscle-related side effects, with myopathy being characterized by muscle pain, weakness, or even damage in more severe cases. The occurrence of myopathy, particularly rhabdomyolysis, can lead to elevated creatine kinase levels and potential kidney damage if not monitored and managed properly.

While fatigue, diarrhea, and headache can also occur in some patients taking statins, myopathy stands out due to its specific association with the pharmacological action of these drugs and its potential severity, warranting careful monitoring in patients who are prescribed statins. This highlights the importance of understanding the side effect profiles of lipid-lowering agents in clinical practice.