For which condition are omega-3 fatty acids specifically indicated?

Omega-3 fatty acids are specifically indicated for the treatment of severe hypertriglyceridemia. This condition is characterized by extremely high levels of triglycerides in the bloodstream, which can significantly increase the risk of cardiovascular diseases. Omega-3 fatty acids have been shown in multiple studies to effectively lower triglyceride levels by reducing hepatic triglyceride production and increasing the clearance of triglycerides from the blood.

While omega-3 fatty acids can have favorable effects on various lipid profiles, such as modestly raising HDL cholesterol and possibly having some anti-inflammatory effects, their primary and most well-supported use is in reducing high triglyceride levels. This makes them particularly useful in patients with severe hypertriglyceridemia, where other standard lipid-lowering therapies may not be sufficient or appropriate.