Before starting statin therapy, which laboratory value should be assessed in a client?

Assessing liver function tests (LFTs) before starting statin therapy is crucial because statins can affect liver enzymes. Statins are primarily metabolized in the liver, and there is a potential risk of hepatotoxicity associated with their use. Evaluating LFTs helps to establish a baseline for liver function and to identify any pre-existing liver conditions that could contraindicate the use of statins or require close monitoring.

If LFTs show elevated liver enzymes before the initiation of therapy, healthcare providers can make more informed decisions about whether to start the medication or to select an alternative treatment strategy. This step is part of ensuring the safety and efficacy of statin therapy for lipid management. Monitoring liver function during statin treatment is also recommended to catch any arising issues early on, reinforcing the importance of assessing LFTs prior to commencing therapy.